Recombinant Human TM protein-Recombinant Protein-Biotyscience

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Recombinant Human TM protein

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Cat No	ADMD-025
Conjugate
Type	重组蛋白
Source	E.Coli
Tag	N/A
Size	1mg
Application	Immunology
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS
Species	Human
Storage	Store at -20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	Thrombomodulin;CD141;CD141 antigen;Fetomodulin;THBD;THRM;TM;AHUS 6;AHUS6;BDCA 3;BDCA3;THPH12;TRBM_HUMAN.
Purification	Protein A/G
MolecularWeight
Description
Background	Thrombomodulin, TM is cell surface glycoprotein; Plays an important role in the protein C anticoagulant pathway. It located in a vein, artery and capillary endothelial cells on the surface of plasma membrane protein. It is generally believed: TM vascular endothelial injury is an important parameter is the thrombin receptor, known in a variety of normal human tissues, can also be expressed in many tumors, TM may be similar to the E-cadherin,and is a lectin Like activity of a new class of members of the cell adhesion molecules. CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; Thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human TM protein