Recombinant Human Factor VIII protein,His-Recombinant Protein-Biotyscience

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Recombinant Human Factor VIII protein,His

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Cat No	ADMD-042
Conjugate
Type	重组蛋白
Source	E. coli
Tag	His
Size	50ug
Application	Immunology
Format	Liquid
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 g/L as determined by microplate BCA method
Buffer	50 mM Tris-HCl, pH 8.0, 8 M urea
Species	Human
Storage	Store at -80 °C.
Synonyms	AHF;DXS1253E;F8B;F8C;FVIII;HEMA
Purification	Protein A
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
MolecularWeight	24.5 kDa
Description
Background	This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human Factor VIII protein,His