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Cat No | ADMD-058 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | Fc,Myc,His |
Size | 1mg |
Application | Immunology |
Format | Liquid |
Purity | >95?%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Human |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD28, Tp44 |
Purification | Protein A/G |
Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
MolecularWeight | 43.6 kDa |
Description | |
Background | Cluster of Differentiation 28 (CD28, also known as Tp44) is one of the proteins constitutively expressed on the surface of 80% of human T cells. CD28 is a highly glycosylated membrane protein, formed by two homodimer disulfide-linked peptides, which shares homology with the immunoglobulin superfamily. CD28 signals play a key role in many T cell processes including cytoskeletal remodeling, production of cytokines, survival, and differentiation. CD28 interactions with the B7 family of costimulatory ligands are essential for initiating antigen-specific T cell responses, upregulating cytokine expression and promoting T cell expansion and differentiation. |