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Recombinant Human LIGHT/TNFSF14 protein,His

Cat NoADMD-075
Conjugate
Type重组蛋白
SourceHEK293
TagHis
Size1mg
ApplicationImmunology
FormatLiquid
Purity>95 %, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS
SpeciesHuman
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCD258, HVEML, HVEM-L, LIGHT, LTg, TNFSF14, TR2
PurificationProtein A/G
NoteFor research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight19 kDa
Description
BackgroundTumor necrosis factor superfamily member 14 (TNFSF14), LIGHT, is a component of the cytokine network that regulates innate and adaptive immune responses, which promote homeostasis of lymphoid organs, liver, and bone. TNFSF14 is an immunomodulatory cytokine and a member of the TNF superfamily. It is expressed by lymphocytes, monocytes, and granulocytes, and is primarily known for its critical role in immune functions. TNFSF14 leads to T cell activation through interaction with HVEM by enhancing T cell proliferation and induces cytokine secretion through binding to lymphotoxin β receptor (LTβR) on mast cells. TNFSF14 has also been implicated in various pathogenic conditions related to inflammatory responses such as tumors, type 2 diabetes, and atherosclerosis.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.