Recombinant Human PDGFR beta protein,Myc,His-Recombinant Protein-Biotyscience

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Antibodies
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- Secondary Antibodies
- ELISA Kit
  - --|--|Conjugation Kit
Protein
Bioparticles
- Metal Nanoparticles
  - --|--|Gold Nanoparticles
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  - --|--|PS Magnetic Particles
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  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
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  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|Magnetic Separation
- Monodisperse Particles
  - --|--|Polystyrene Particles
  - --|--|Silica Particles
  - --|--|PMMA Particles
  - --|--|PET Particles
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  - --|--|DVB Particles
  - --|--|PP Particles
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  - --|--|PDLA Particles
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- Other Particles
  - --|--|Upconverting Nanoparticles
  - --|--|Quantum dots
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  - --|--|Chromatography Media
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Recombinant Human PDGFR beta protein,Myc,His

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Cat No	ADMD-081
Conjugate
Type	重组蛋白
Source	HEK293
Tag	Myc,His
Size	1mg
Application	Immunology
Format	Liquid
Purity	>90 %, SDS-PAGE
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS
Species	Human
Storage	Store at -20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	CD140B, JTK12, PDGF R beta, PDGFR, PDGFR beta, PDGFR1, PDGFRB
Purification	Protein A/G
Note	For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
MolecularWeight	58.8 kDa
Description
Background	Multiple receptor tyrosine kinases and their growth factor ligands have been implicated in cancer progression and metastasis. Among these are the platelet-derived growth factor receptors (PDGFRs). Expression of PDGFRs is mainly restricted to mesenchymal cell types. PDGF is composed of homo-dimers or hetero-dimers of two polypeptide chains, denoted A and B. The two receptor subtypes show different affinities for the dimeric PDGF isoforms. In epithelial tumors, the platelet-derived growth factor receptor B (PDGFRB, also known as PDGFR beta) is mainly expressed by stromal cells of mesenchymal origin. it has also been shown that PDGFRB is also associated with the aggressive behavior of several types of tumors. The 60% of colon cancer patients express high levels of this gene and the PDGFRB expression correlates with lymphatic dissemination of this cancer. Furthermore, PDGFRB signaling in mesenchymal-like tumor cells (as colorectal cancer cells) contributes to invasion and liver metastasis formation.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human PDGFR beta protein,Myc,His