Recombinant Human HER2/ErbB2 Protein(aa 23-652), His-Recombinant Protein-Biotyscience

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Recombinant Human HER2/ErbB2 Protein(aa 23-652), His

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Cat No	BIOP1812
Conjugate
Type	CAR-T相关
Source	HEK293
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS, pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	CD340;HER-2;HER-2/neu;HER2;MLN 19;MLN19;NEU;NGL;TKR1
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 23-652
Background	Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. ErbB2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human HER2/ErbB2 Protein(aa 23-652), His