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Recombinant Mouse TNFSF11/RANK L/TRANCE Protein(aa 137-316)

Cat NoBIOP1972
Conjugate
TypeTNF
SourceE. coli
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 20mM PB, 150mM NaCl, pH 7.4.
SpeciesMouse
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsTumor necrosis factor ligand superfamily member 11;Tnfsf11;Osteoclast differentiationfactor;ODF;Osteoprotegerin ligand;OPGL;Receptor activator of nuclear factor kappa-Bligand;RANKL;TNF-related activation-induced cytokine;TRANCE;CD254
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 137-316
BackgroundMouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor(TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such asthymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involvedin a number of fundamental biological processes such as acting as regulator of interactions between T-cells anddendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption inhumoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cellproliferation.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.