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Recombinant Mouse TNFSF4/OX40 Ligand Protein(aa 51-198), His

Cat NoBIOP1976
Conjugate
TypeTNF
SourceHEK293
TagHis
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesMouse
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsTumor necrosis factor ligand superfamily member 4;TNFSF4;CD134 ligand;CD134L;CD252;CD252 antigen;OX40 antigen ligand;OX40 ligand;OX40L;TAX transcriptionally-activatedglycoprotein 1;tumor necrosis factor (ligand) superfamily;member 4
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 51-198
BackgroundOX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptorsuperfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival andfor the generation of memory T cells from activated effector T cells. OX40L – OX40 co-stimulation leads toactivation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong thesurvival of effector CD4+Th cells as well as contributes to generation of memory T cells.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.