Recombinant Human 4-1BB Ligand/TNFSF9 Protein(aa 71-254), His-Recombinant Protein-Biotyscience

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Recombinant Human 4-1BB Ligand/TNFSF9 Protein(aa 71-254), His

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Cat No	BIOP2210
Conjugate
Type	免疫检查点
Source	E. coli
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 50mM Tris, 150mM NaCl, pH 8.0.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	4-1BB-L;CD137L;TNLG5A
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 71-254
Background	The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human 4-1BB Ligand/TNFSF9 Protein(aa 71-254), His