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Cat No | BIOP2405 |
Conjugate | |
Type | 其他蛋白 |
Source | E. coli |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | A-FABP;AFABP;ALBP;aP2;HEL-S-104 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 2-132 |
Background | Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein. It is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients. |