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Cat No | BIOP2448 |
Conjugate | |
Type | 其他蛋白 |
Source | HEK293 |
Tag | Fc-His |
Size | 50 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | PERB11.2 |
Purification | > 97% by SDS-PAGE. |
MolecularWeight | |
Description | aa 23-298 |
Background | This protein is a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. |