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Cat No | BIOP2940 |
Conjugate | |
Type | 生物标志物 |
Source | HEK293 |
Tag | Fc-His |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. Normally 5 % - 41 % trehalose is added as protectants before lyophilization. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | CD86;B7-2;B70;CD28LG2;LAB72;MGC34413 |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 26-247 |
Background | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |