Recombinant Human BMP-7 Protein, His-Recombinant Protein-Biotyscience

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Recombinant Human BMP-7 Protein, His

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Cat No	BIOP3472
Conjugate
Type	细胞因子
Source	E. coli
Tag	His
Size	20 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	BMP7;OP-1
Purification	> 98% by SDS-PAGE.
MolecularWeight
Description
Background	BMP-7 (Bone morphogenetic protein 7) is a bone morphogenetic protein which belongs to the TGF-β superfamily. OP-1 is expressed in the brain, kidneys, and bladder. BMP-7 may be involved in bone homeostasis and plays a key role in the transformation of mesenchymal cells into bone and cartilage. The phosphorylation of SMAD1 and SMAD5 can be induced by BMP-7, which in turn induce transcription of numerous osteogenic genes. BMP-7 treatment can also induce all of the genetic markers of osteoblast differentiation in many cell types. Human recombinant BMP-7 protein can be used to aid in the fusion of vertebral bodies to prevent neurologic trauma. It also functions in the treatment of tibial non-union, frequently in cases where a bone graft has failed. It is found that BMP7 has the potential for treatment of chronic kidney disease.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human BMP-7 Protein, His