Recombinant Human PVRL4/Nectin-4/PRR4/LNIR Protein(aa 31-351), His-Recombinant Protein-Biotyscience

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Recombinant Human PVRL4/Nectin-4/PRR4/LNIR Protein(aa 31-351), His

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Cat No	BIOP3626
Conjugate
Type	药物靶点
Source	HEK293
Tag	His
Size	10 ug
Application	Immunogen
Format	Lyophilized
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 20mM PB,150mM NaCl,pH 7.4.
Species	Human
Storage	Store at –20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	PVRL4;Nectin-4;Ig superfamily receptor LNIR;Poliovirus receptor-related protein 4;PRR4;LNIR
Purification	> 95% by SDS-PAGE.
MolecularWeight
Description	aa 31-351
Background	Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamilyproteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved incell adhesion through trans-homophilic and -heterophilic interactions, the latter including specificallyinteractions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantlyexpressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium.The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17.Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomalrecessive disorder.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Recombinant Human PVRL4/Nectin-4/PRR4/LNIR Protein(aa 31-351), His