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Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(aa 100-233), His

Cat NoBIOP3632
Conjugate
Type药物靶点
SourceHEK293
TagHis
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsNKG2-A/NKG2-B type II integral membrane protein;CD159 antigen-like family member A;NK cellreceptor A;NKG2-A/B-activating NK receptor;CD159a;KLRC1;NKG2A
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 100-233
BackgroundNKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killercell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteinspreferentially expressed in NK cells. Members of this proteins is characterized by the type II membraneorientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells orB-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B,NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing aC-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NKcells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in thenomenclature of CD antigens.
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