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Cat No | BIOP3661 |
Conjugate | |
Type | 药物靶点 |
Source | HEK293 |
Tag | Fc |
Size | 10 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. Normally 5 % - 42 % trehalose is added as protectants before lyophilization. |
Species | Human |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | TNFRSF17;CD269;BCM;BCMA |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | aa 1-54 |
Background | B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK. |