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Recombinant Protein

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CCP Antigen

Cat NoBSA-0047A
Conjugate
Type重组蛋白
SourceSynthetic
Size1 mg
ApplicationImmunogen; Calibrator; Standard
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in 0.01 M PBS, pH 7.4, 0.1% Proclin300.
StorageStore at -20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCyclic Citrullinated Peptide;CCP;环瓜氨酸肽;277748-59-1;Cycliccitrullinatedpeptide;HQCHQESTXGRSRGRCGRSGS Disulfide bond
Purification> 96% by HPLC
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundRheumatoid arthritis (RA) is an autoimmune disease characterized by erosive arthritis and has a high teratogenic rate. High disability rate; In 2000, Dutch scholar Schellekens et al. reported for the first time that synthetic cyclic citrullinated peptide (CCP) was used as an antigen to detect antibodies in sera of RA patients. Anti-ccp antibodies are secreted spontaneously by B lymphocytes of patients with rheumatoid arthritis, but not by B lymphocytes of patients with other diseases and normal people. Using CCP as antigenic matrix to detect anti-CCP antibodies in serum of rheumatoid patients has high sensitivity (50%) and specificity (96%) for rheumatoid arthritis (RA), which is a highly specific index for the early diagnosis of RA.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.