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Cat No | BSA-1028 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | His |
Size | 1mg |
Application | Immunology |
Purity | ≥95%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS with 6% Mannitol, pH7.4. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | COSLG;B7-H2;B7H2;B7RP-1;B7RP1;CD275;GL50;ICOS-L;ICOSL;LICOS;ICOS ligand |
Purification | Chromatography |
MolecularWeight | 28.4kD |
Description | 内毒素<0.1EU/ug |
Background | ICOSLG contains an immunoglobulin-like c2-type domain and an immunoglobulin-like v-type domain. Subtype 1 is ubiquitously expressed, whereas subtype 2 was only detected only in lymph nodes, leukocytes, and spleen. B7-H2 is a ligand for the T cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T cell proliferation and cytokine secretion, and induces B cell proliferation and differentiation into plasma cells. |