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Cat No | BSA-1077 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | Fc |
Size | 1mg |
Application | Immunology |
Purity | > 90%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | bone morphogenetic protein 2;BMP 2;BMP 2A;BMP2;BMP2A;BMP-2;BMP2_HUMAN |
Purification | Chromatography |
MolecularWeight | 39.8kD |
Description | 内毒素<0.1 EU/ug |
Background | This protein is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. |