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Rabbit Anti-GAB2 Polyclonal Antibody

Cat NoBSPA-1907
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsGAB2;GRB2-associated binding protein 2;GRB2-associated-binding protein 2;Grb2 associated binder 2;KIAA0571;pp100;Grb2-associated binder 2;growth factor receptor bound protein 2-associated protein 2
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThis gene is a member of the GRB2-associated binding protein gene family. These proteins contain pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.