Biotyscience Inc
E-mail biotyscience@gmail.com
info@biotyscience.com
Tel 400-669-8850
Cat No | BSMA-0702-D |
Conjugate | |
Type | 抗体对 |
Source | Mouse |
Size | 1 mg |
Application | TRFIA; CLIA |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | MMP-3;基质金属蛋白酶3;CHDS6;Matrix metalloproteinase 3;Matrix metalloproteinase 3 preproprotein;Matrix metalloproteinase-3;MGC126102;MGC126103;MGC126104;MMP 3;MMP-3;MMP3;MMP3_HUMAN;Proteoglycanase;SL-1;SL1;STMY;STMY1;STR1;Stromelisin 1;Stromelysin 1;Stromelysin 1 progelatinase;Stromelysin-1;Transin 1;Transin-1 |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | Recommended Antibody pairs: BSMA-0702-C- BSMA-0702-D |
Background | Matrix metalloproteinase (matrix metalloproteinase), matrix metalloproteinase is a large family, because of its need for Ca2+; Metal ions such as Zn2+ are named as cofactors. The family members have similar structures and are generally composed of five functional domains :(1) hydrophobic signal peptide sequences; (2) The propeptide region, whose main function is to maintain the stability of the zymogen. When this region was cut off by exogenous enzymes, MMPs zymogen was activated. (3) Catalytic active zone, zinc ion binding site, is very important for the play of enzyme catalysis; (4) proline-rich hinge region; (5) carboxyl terminal region, which is related to the substrate specificity of the enzyme. The catalytic activity region and propeptide region of the enzyme are highly conserved. MMPs members have their own characteristics based on the above structures. There is some substrate specificity among various MMP, but it is not absolute. The same MMP can degrade a variety of extracellular matrix components, and a certain extracellular matrix component can be degraded by a variety of MMP, but the degradation efficiency of different enzymes is different. |