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Cat No | ABMY036 |
Conjugate | |
Type | 单克隆抗体 |
Source | Mouse |
Tag | N/A |
Size | 100 ul |
Application | WB; IHC-P; IHC-F; ICC; IF; Flow-Cyt; ELISA |
ApplicationNote | WB 1:500-2000; IHC-P 1:100-500; IHC-F 1:100-500; ICC 1:100-500; IF 1:100-500; Flow-Cyt 1ug/Test; ELISA 1:5000-10000 |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 0.01M TBS(pH=7.4) |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | platelet glycoprotein IIb of IIb/IIIa complex;Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41);GPIIb;GTA;HPA3;CD 41;CD41 antigen;CD41a;CD41b;GP2b;GPalpha IIb;GPalphaIIb;Integrin alpha IIb;Integrin alpha IIb precursor;ITGA 2B;Integrin alpha 2b;ITGAB;Platelet fibrinogen receptor alpha;Platelet fibrinogen receptor alpha subunit;Platelet glycoprotein IIb of IIb/IIIa complex;Platelet membrane glycoprotein IIb;Platelet specific antigen bak;ITA2B_HUMAN |
Purification | Affinity purified by Protein G |
MolecularWeight | 125 kDa |
Description | |
Background | his gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. |