Rabbit anti-Human Presenilin 1 Monoclonal Antibody-Monoclonal Antibody-Biotyscience

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Antibodies
- Primary Antibodies
  - --|--|Monoclonal Antibody
  - --|--|Polyclonal Antibody
  - --|--|Small Molecule Antibody
  - --|--|Antibody Pairs
- Secondary Antibodies
- ELISA Kit
  - --|--|Conjugation Kit
Protein
Bioparticles
- Metal Nanoparticles
  - --|--|Gold Nanoparticles
  - --|--|Gold Nanorods
  - --|--|Silver Nanoparticles
  - --|--|Gold NanoUrchins
  - --|--|Carbon Nanoparticles
  - --|--|Special Shape Particles
- Magnetic Particles
  - --|--|PS Magnetic Particles
  - --|--|Silica Magnetic Particles
  - --|--|Fe3O4 Magnetic Particles
  - --|--|Functionalized Magnetic Particles
  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
  - --|--|Magrose Magnetic Particles
  - --|--|UF Magnetic Particles
  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|Magnetic Separation
- Monodisperse Particles
  - --|--|Polystyrene Particles
  - --|--|Silica Particles
  - --|--|PMMA Particles
  - --|--|PET Particles
  - --|--|PVA Particles
  - --|--|PVC Particles
  - --|--|DVB Particles
  - --|--|PP Particles
  - --|--|PE Particles
  - --|--|GMA Particles
  - --|--|PLA Particles
  - --|--|PCL Particles
  - --|--|PLLA Particles
  - --|--|PDLA Particles
  - --|--|PLGA Particles
  - --|--|PTFE Particles
  - --|--|PBS Particles
- Other Particles
  - --|--|Upconverting Nanoparticles
  - --|--|Quantum dots
  - --|--|Fluorescent Particles
  - --|--|Chromatography Media
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Rabbit anti-Human Presenilin 1 Monoclonal Antibody

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Documentation
Citations

Cat No	BMA-1017
Conjugate
Type	重组兔多抗
Source	Rabbit
Size	50 uL
Application	Immunogen
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	AD3;FAD;PS-1;PS1;S182;Presenilin 1;PSEN1
Purification	Affinity purification
MolecularWeight	30kDa/46kDa
Description
Background	Alzheimers disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit anti-Human Presenilin 1 Monoclonal Antibody