Rabbit anti-Human HLA-DRB4 Monoclonal Antibody-Monoclonal Antibody-Biotyscience

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Antibodies
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  - --|--|Monoclonal Antibody
  - --|--|Polyclonal Antibody
  - --|--|Small Molecule Antibody
  - --|--|Antibody Pairs
- Secondary Antibodies
- ELISA Kit
  - --|--|Conjugation Kit
Protein
Bioparticles
- Metal Nanoparticles
  - --|--|Gold Nanoparticles
  - --|--|Gold Nanorods
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  - --|--|Gold NanoUrchins
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- Magnetic Particles
  - --|--|PS Magnetic Particles
  - --|--|Silica Magnetic Particles
  - --|--|Fe3O4 Magnetic Particles
  - --|--|Functionalized Magnetic Particles
  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
  - --|--|Magrose Magnetic Particles
  - --|--|UF Magnetic Particles
  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|Magnetic Separation
- Monodisperse Particles
  - --|--|Polystyrene Particles
  - --|--|Silica Particles
  - --|--|PMMA Particles
  - --|--|PET Particles
  - --|--|PVA Particles
  - --|--|PVC Particles
  - --|--|DVB Particles
  - --|--|PP Particles
  - --|--|PE Particles
  - --|--|GMA Particles
  - --|--|PLA Particles
  - --|--|PCL Particles
  - --|--|PLLA Particles
  - --|--|PDLA Particles
  - --|--|PLGA Particles
  - --|--|PTFE Particles
  - --|--|PBS Particles
- Other Particles
  - --|--|Upconverting Nanoparticles
  - --|--|Quantum dots
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  - --|--|Chromatography Media
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Rabbit anti-Human HLA-DRB4 Monoclonal Antibody

Description
Documentation
Citations

Cat No	BMA-2072
Conjugate
Type	重组兔多抗
Source	Rabbit
Size	50 uL
Application	WB; FC; ELISA
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.09% sodium azide, pH7.4.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	HLA-DRB4;DR4;DRB4;HLA-DR4B;major histocompatibility complex;class II;DR beta 4
Purification	Affinity purification
MolecularWeight	30KDa
Description
Background	Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit anti-Human HLA-DRB4 Monoclonal Antibody