Biotyscience Inc
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Cat No | BMA-2074 |
Conjugate | |
Type | Monoclonal Antibody |
Source | Mouse |
Size | 50 uL |
Application | WB; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium azide. |
Species | Human |
Storage | Store at 4℃. Avoid freeze / thaw cycles. |
Synonyms | COCA2;FCC2;HNPCC;HNPCC2;hMLH1 |
Purification | Affinity purification |
MolecularWeight | 85KDa |
Description | |
Background | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. |