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Mouse anti-Human MLH1 Monoclonal Antibody

Cat NoBMA-2074
Conjugate
TypeMonoclonal Antibody
SourceMouse
Size50 uL
ApplicationWB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in Tris Buffer, pH7.3-7.7, with 1% BSA and <0.1% Sodium azide.
SpeciesHuman
StorageStore at 4℃. Avoid freeze / thaw cycles.
SynonymsCOCA2;FCC2;HNPCC;HNPCC2;hMLH1
PurificationAffinity purification
MolecularWeight85KDa
Description
BackgroundThis gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.