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Rabbit anti-SARS-CoV-2 SARS-CoV-2 Spike S1 Monoclonal Antibody
- Description
- Documentation
- Citations
| Cat No | BMA-2344 |
| Conjugate | |
| Type | 重组兔多抗 |
| Source | Rabbit |
| Size | 50 uL |
| Application | WB; IHC |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Species | SARS-CoV-2 |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Synonyms | |
| Purification | Affinity purification |
| MolecularWeight | 110KDa |
| Description | |
| Background | The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Its been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.