Rabbit anti-Human E2F1 Monoclonal Antibody-Monoclonal Antibody-Biotyscience

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  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
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  - --|--|Conjugation Kit
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  - --|--|Polystyrene Particles
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  - --|--|Quantum dots
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  - --|--|Chromatography Media
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Rabbit anti-Human E2F1 Monoclonal Antibody

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Cat No	BMA-711
Conjugate
Type	重组兔多抗
Source	Rabbit
Size	50 uL
Application	Immunogen
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.02% sodium azide, 0.05% BSA,50% glycerol, pH7.3.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	E2F-1;RBAP1;RBBP3;RBP3;E2F1
Purification	Affinity purification
MolecularWeight	70KDa
Description
Background	The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit anti-Human E2F1 Monoclonal Antibody