Mouse anti-Human E-Cadherin Monoclonal Antibody-Monoclonal Antibody-Biotyscience

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Mouse anti-Human E-Cadherin Monoclonal Antibody

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Cat No	BMA-928
Conjugate
Type	Monoclonal Antibody
Source	Mouse
Size	50 uL
Application	WB; IF
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	Arc-1;CD324;CDHE;ECAD;LCAM;UVO;CDH1;E-Cadherin
Purification	Affinity purification
MolecularWeight	120kDa
Description
Background	This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Mouse anti-Human E-Cadherin Monoclonal Antibody