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Cat No | BMM-020 |
Conjugate | |
Type | 单克隆抗体 |
Clone | T02 |
Source | CHO |
Tag | N/A |
Size | 1mg |
Application | Immunology |
Purity | >95%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | CD16;CD16A;Fc gamma RIII alpha;FCG3;FCGR3;FCGR3A;FCGRIII;FCRIII;FCRIIIA;IGFR3 |
Purification | ProteinA |
MolecularWeight | |
Description | 内毒素<0.01EU/ug |
Background | CD16, also known as the low affinity Fc gamma receptor III for IgG (FcγRIII), exists in two isoforms, FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. CD16a is expressed on NK cells, macrophages, and placental trophoblasts as a polypeptide-anchored transmembrane protein while CD16b is expressed on neutrophils in a glycosylphosphatidylinositol (GPI)-anchored form. CD16a forms a heteromeric structure with the Fc epsilon RI (gamma) and/or CD3 (zeta) subunits. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |