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Cat No | BMM-026 |
Conjugate | |
Type | 单克隆抗体 |
Clone | T08 |
Source | CHO |
Tag | N/A |
Size | 1mg |
Application | Immunology |
Purity | >90%, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Storage | Store at -20 degree for long time. Avoid repeated freeze/thaw cycles. |
Synonyms | Erb-B2 Receptor Tyrosine Kinase 2;HER2;NGL;NEU;V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2;Tyrosine Kinase-Type Cell Surface Receptor HER2;Neuro/Glioblastoma Derived Oncogene Homolog;Human Epidermal Growth Factor Receptor 2;Metastatic Lymph Node Gene 19 Protein;Proto-Oncogene C-ErbB-2 |
Purification | ProteinA |
MolecularWeight | |
Description | 内毒素<0.1EU/ug |
Background | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |