Mouse Anti-GFAP Monoclonal Antibody (Fluor 488), clone SA-004-Monoclonal Antibody-Biotyscience

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Mouse Anti-GFAP Monoclonal Antibody (Fluor 488), clone SA-004

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Citations

Cat No	BSMA-0052
Conjugate
Type	Monoclonal Antibody
Source	Mouse
Tag	Fluor 488
Size	100 ug
Application	IF
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in 0. 02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68. 98% PBS.
Storage	Store at -20 degree. Avoid repeated freeze/thaw cycles.
Synonyms	fb34h11;ALXDRD;cb345;etID36982. 3;FLJ42474;FLJ45472;GFAP;GFAP_HUMAN;gfapl;Glial fibrillary acidic protein;Intermediate filament protein;wu: fk42c12;xx: af506734;zgc: 110485
Purification	Protein G affinity purified.
Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight	50 kDa
Description
Background	Glial fibrillary acidic protein (GFAP) is an intermediate filament protein. The protein is the smallest (8 nm) of the intermediate filament proteins with a molecular weight of about 51 kDa. In the central nervous system, GFAP is expressed in astrocytes and ependymal cells but not in other glial cells. However, immature oligodendrocytes and immature choroid plexus cells may be GFAP positive. In the peripheral nervous system enteric Schwann cells and satellite cells of human sensory ganglia express GFAP. Outside the nervous system, GFAP is seen in myoepithelial cells and chondroblasts, in the former coexpressed with cytokeratin, in the latter coexpressed with vimentin. Astrocytoma, ependymoma, glioblastoma, and oligodendroglioma are almost always positive. Plexus carcinoma, ganglioglioma and primitive neuroectodermal tumours (PNET: neuroblastoma a.o.) express GFAP to a varying extent. Schwannoma and neurofibroma frequently express GFAP. Chondroma, chondrosarcoma and pleomorphic adenoma are also GFAP positive in most cases. A few carcinomas (especially from lung and breast) may express GFAP. in paraganglioma GFAP may be detected in sustentacular cells.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Mouse Anti-GFAP Monoclonal Antibody (Fluor 488), clone SA-004