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Rabbit Anti-Cytokeratin 9 Monoclonal Antibody (Fluor 488), clone SA-025
- Description
- Documentation
- Citations
| Cat No | BSMA-0073 |
| Conjugate | |
| Type | Recombinant Rabbit Monoclonal Antibody |
| Source | Rabbit |
| Tag | Fluor 488 |
| Size | 100 ug |
| Application | IF |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in 0. 02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68. 98% PBS. |
| Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
| Synonyms | CK 9;CK-9;Cytokeratin 9;Cytokeratin-9;Cytokeratin9;EPPK;K1C9_HUMAN;K9;Keratin 9;Keratin;Keratin type I cytoskeletal 9;Keratin-9;Keratin9;KRT 9;Krt9;Spermatid Perinuclear Ring Manchette Protein K9;type I cytoskeletal 9 |
| Purification | Protein A affinity purified. |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | 62 kDa |
| Description | |
| Background | Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.