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Rabbit Anti-Cytokeratin 15 Monoclonal Antibody (Fluor 488), clone SA-028
- Description
- Documentation
- Citations
| Cat No | BSMA-0076 |
| Conjugate | |
| Type | Recombinant Rabbit Monoclonal Antibody |
| Source | Rabbit |
| Tag | Fluor 488 |
| Size | 100 ug |
| Application | IF, ICC |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in 0. 02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68. 98% PBS. |
| Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
| Synonyms | AI528832;CK 15;CK-15;CK15;Cytokeratin-15;Cytokeratin15;K15;K1C15_HUMAN;K1CO;Ka15;Keratin 15;Keratin 15 basic;Keratin 15 beta;Keratin;Keratin complex 1 acidic gene 15;Keratin type I cytoskeletal 15;Keratin-15;Keratin15;KRT 15;Krt1-15;KRT15;KRTB;KRTL15;Type I cytoskeletal 15;Type I keratin Ka15 |
| Purification | Protein A affinity purified. |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | 49 kDa |
| Description | |
| Background | Cytokeratin 15 (CK15, K15, K1CO, keratin15, type I cytoskeletal 15) is an intermediate filament (IF) type I protein that is responsible for the mechanical integrity of epithelial cells. Keratin family members are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains, and are clustered in a region on chromosome 17q21.2. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceus. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.