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Rabbit Anti-Cytokeratin 7 Monoclonal Antibody (Fluor 647), clone SA-036
- Description
- Documentation
- Citations
| Cat No | BSMA-0084 |
| Conjugate | |
| Type | Recombinant Rabbit Monoclonal Antibody |
| Source | Rabbit |
| Tag | Fluor 647 |
| Size | 100 ug |
| Application | ICC, IF |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in 0. 02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68. 98% PBS. |
| Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
| Synonyms | CK 7;CK-7;CK7;Cytokeratin 7;Cytokeratin-7;D15Wsu77e;K2C7;K2C7_HUMAN;K7;Keratin 7;Keratin 7, type II;Keratin type II cytoskeletal 7;Keratin, 55K type II cytoskeletal;Keratin, simple epithelial;Keratin, simple epithelial type I, K7;Keratin, type II cytoskeletal 7;Keratin-7;Krt2-7;KRT7;MGC11625;MGC129731;MGC3625;Sarcolectin;SCL;Type II mesothelial keratin K7;Type-II keratin Kb7 |
| Purification | Protein A affinity purified. |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | 51 kDa |
| Description | |
| Background | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. Cytokeratin 7 (also known as sarcolectin) agglutinates normal and transformed cells with a high affinity for simple sugars. Cytokeratin 7 also inhibits the synthesis of interferon-dependent secondary proteins thus reversing the antiviral effect of interferon induction and restoring cells to their status ad primum. In normal and transformed cells, Cytokeratin 7 localizes to the membrane. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.