Content
Contact us
Biotyscience Inc
E-mail biotyscience@gmail.com
info@biotyscience.com
Tel 400-669-8850
Rabbit Anti-Cytokeratin 16 Monoclonal Antibody (Fluor 647), clone SA-040
- Description
- Documentation
- Citations
| Cat No | BSMA-0088 |
| Conjugate | |
| Type | Recombinant Rabbit Monoclonal Antibody |
| Source | Rabbit |
| Tag | Fluor 647 |
| Size | 100 ug |
| Application | IF |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in 0. 02% Sodium azide Constituents: 30% Glycerol, 1% BSA, 68. 98% PBS. |
| Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
| Synonyms | CK 16;CK-16;Cytokeratin-16;Cytokeratin16;FNEPPK;Focal non epidermolytic palmoplantar keratoderma;K 16;K16;K1C16_HUMAN;K1CP;Keratin 1 type I;Keratin 16;Keratin;Keratin type I cytoskeletal 16;Keratin-16;Keratin16;KRT 16;Krt16;KRT16A;NEPPK;PC1;type I cytoskeletal 16 |
| Purification | Protein A affinity purified. |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | 51 kDa |
| Description | |
| Background | Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in noninvasive breast carcinomas and normal breast tissue. Mutations in the Cytokeratin 16 gene cause various diseases, including pachyonychia congenita type 1 (PC1), nonepidermolytic palmoplantar keratoderma (NEPPK) and unilateral palmoplantar verrucous nevus (UPVN). |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.