Rabbit Anti-EXOSC10 Polyclonal Antibody-Products-Biotyscience

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Antibodies
- Primary Antibodies
  - --|--|Monoclonal Antibody
  - --|--|Polyclonal Antibody
  - --|--|Small Molecule Antibody
  - --|--|Antibody Pairs
- Secondary Antibodies
- ELISA Kit
  - --|--|Conjugation Kit
Protein
Bioparticles
- Metal Nanoparticles
  - --|--|Gold Nanoparticles
  - --|--|Gold Nanorods
  - --|--|Silver Nanoparticles
  - --|--|Gold NanoUrchins
  - --|--|Carbon Nanoparticles
  - --|--|Special Shape Particles
- Magnetic Particles
  - --|--|PS Magnetic Particles
  - --|--|Silica Magnetic Particles
  - --|--|Fe3O4 Magnetic Particles
  - --|--|Functionalized Magnetic Particles
  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
  - --|--|Magrose Magnetic Particles
  - --|--|UF Magnetic Particles
  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|Magnetic Separation
- Monodisperse Particles
  - --|--|Polystyrene Particles
  - --|--|Silica Particles
  - --|--|PMMA Particles
  - --|--|PET Particles
  - --|--|PVA Particles
  - --|--|PVC Particles
  - --|--|DVB Particles
  - --|--|PP Particles
  - --|--|PE Particles
  - --|--|GMA Particles
  - --|--|PLA Particles
  - --|--|PCL Particles
  - --|--|PLLA Particles
  - --|--|PDLA Particles
  - --|--|PLGA Particles
  - --|--|PTFE Particles
  - --|--|PBS Particles
- Other Particles
  - --|--|Upconverting Nanoparticles
  - --|--|Quantum dots
  - --|--|Fluorescent Particles
  - --|--|Chromatography Media
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Rabbit Anti-EXOSC10 Polyclonal Antibody

Description
Documentation
Citations

Cat No	BSPA-1840
Conjugate
Type	Polyclonal Antibody
Source	Rabbit
Size	1 mg
Application	ELISA; WB
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS.
Species	Human
Storage	Store at -20 degree. Avoid repeted freeze/thaw cycl.
Synonyms	EXOSC10;exosome component 10;PMSCL2, polymyositis/scleroderma autoantigen 2, 100kDa;p2;p3;p4;PM Scl;PM/Scl 100;polymyositis/scleroderma autoantigen 2;RRP6;Rrp6p;autoantigen PM-SCL;autoantigen PM/Scl 2;polymyositis/scleroderma autoanti
Purification
Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
Background	Putative catalytic component of the RNA exosome complex which has 3, 5 exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding pervasive transcripts, such as anti-sense RNA species and promoter-upstream transcripts , and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination and/or Ig variable region somatic hypermutation by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements within their 3 untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3-5 exonuclease activity . EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Rabbit Anti-EXOSC10 Polyclonal Antibody