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Rabbit Anti-GCK Polyclonal Antibody

Cat NoBSPA-1921
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsGCK;glucokinase;GK;GLK;HK4;HHF3;HKIV;HXKP;LGLK;MODY2;FGQTL3;glucokinase;HK IV;hexokinase-4;hexokinase-D;hexokinase type IV;hexokinase D, pancreatic isozyme;ATP:D-hexose 6-phosphotransferase
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus , maturity onset diabetes of the young, type 2 and persistent hyperinsulinemic hypoglycemia of infancy .
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.