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Rabbit Anti-NLRC4 Polyclonal Antibody

Cat NoBSPA-2351
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsNLRC4;NLR family, CARD domain containing 4;CLAN;IPAF;CLAN1;CLANA;CLANB;CLANC;CLAND;CARD12
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundIn C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains . Human Ced4 homologs include APAF1 , NOD1/CARD4 , and NOD2/CARD15 . These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats . CARD12 is a member of the Ced4 family and can induce apoptosis.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.