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Rabbit Anti-SF3B3 Polyclonal Antibody

Cat NoBSPA-2744
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsSF3B3;splicing factor 3b, subunit 3, 130kDa;splicing factor 3b, subunit 3, 130kD;splicing factor 3B subunit 3;KIAA0017;RSE1;SAP130;SF3b130;SAP 130;spliceosome-associated protein 130;pre-mRNA-splicing factor SF3b 130 kDa subunit;pre-mRNA splicing factor SF3b, 130 kDa subunit;STAF130
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThis gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex . The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA 31-GCN5L acetylase) transcription coactivator-HAT complex, and the TFTC -containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.