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Polyclonal Antibody

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Native Anti-Human CCP Polyclonal Antibody, Serum

Cat NoBIOS-2113P
Conjugate
Type多克隆抗体
SourceSerum
Size1 ml
ApplicationImmunology
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsCyclic Citrullinated Peptide;CCP;环瓜氨酸肽;277748-59-1;Cycliccitrullinatedpeptide;HQCHQESTXGRSRGRCGRSGS Disulfide bond
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundRheumatoid arthritis (RA) is an autoimmune disease characterized by erosive arthritis and has a high teratogenic rate. High disability rate; In 2000, Dutch scholar Schellekens et al. reported for the first time that synthetic cyclic citrullinated peptide (CCP) was used as an antigen to detect antibodies in sera of RA patients. Anti-ccp antibodies are secreted spontaneously by B lymphocytes of patients with rheumatoid arthritis, but not by B lymphocytes of patients with other diseases and normal people. Using CCP as antigenic matrix to detect anti-CCP antibodies in serum of rheumatoid patients has high sensitivity (50%) and specificity (96%) for rheumatoid arthritis (RA), which is a highly specific index for the early diagnosis of RA.
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.