Content
Contact us
Biotyscience Inc
E-mail biotyscience@gmail.com
info@biotyscience.com
Tel 400-669-8850
Rabbit Anti-ANTXR1 Polyclonal Antibody
- Description
- Documentation
- Citations
| Cat No | BSPA-0875 |
| Conjugate | |
| Type | Polyclonal Antibody |
| Source | Rabbit |
| Size | 1 mg |
| Application | ELISA; WB; IHC |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS. |
| Species | Human |
| Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
| Synonyms | ANTXR1;anthrax toxin receptor 1;ATR;GAPO;TEM8;2310008J16Rik;2810405N18Rik;tumor endothelial marker 8;anti-TEM8 |
| Purification | |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | |
| Description | |
| Background | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor and lethal factor disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.