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Rabbit Anti-CASP2 Polyclonal Antibody

Cat NoBSPA-1490
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsCASP2;caspase 2, apoptosis-related cysteine peptidase;ICH1;NEDD2;CASP-2;NEDD-2;PPP1R57;caspase-2;protease ICH-1;protein phosphatase 1, regulatory subunit 57;neural precursor cell expressed developmentally down-regulated protein 2
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThis gene encodes a member of the cysteine-aspartic acid protease family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimers disease, Huntingtons disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.