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Rabbit Anti-EIF2AK3 Polyclonal Antibody

Cat NoBSPA-1812
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsEIF2AK3;eukaryotic translation initiation factor 2-alpha kinase 3;PEK;WRS;PERK;hsPEK;pancreatic EIF2-alpha kinase;PRKR-like endoplasmic reticulum kinase;eukaryotic translation initiation factor 2 alpha kinase 3
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 , leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum , where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.