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Rabbit Anti-POT1 Polyclonal Antibody

Cat NoBSPA-2587
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsPOT1;protection of telomeres 1;HPOT1;protection of telomeres protein 1;protection of telomeres 1 homolog;POT1-like telomere end-binding protein
Purification
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MolecularWeight
Description
BackgroundThis gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.