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Rabbit Anti-PYCARD Polyclonal Antibody
- Description
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- Citations
| Cat No | BSPA-2632 |
| Conjugate | |
| Type | Polyclonal Antibody |
| Source | Rabbit |
| Size | 1 mg |
| Application | ELISA; WB; IHC |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS. |
| Species | Human |
| Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
| Synonyms | PYCARD;PYD and CARD domain containing;ASC;TMS;TMS1;CARD5;TMS-1;apoptosis-associated speck-like protein containing a CARD;target of methylation-induced silencing 1;caspase recruitment domain-containing protein 5 |
| Purification | |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | |
| Description | |
| Background | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain and a C-terminal caspase-recruitment domain . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.