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Rabbit Anti-STAT6 Polyclonal Antibody
- Description
- Documentation
- Citations
| Cat No | BSPA-2817 |
| Conjugate | |
| Type | Polyclonal Antibody |
| Source | Rabbit |
| Size | 1 mg |
| Application | ELISA; WB |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS. |
| Species | Human |
| Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
| Synonyms | STAT6;signal transducer and activator of transcription 6, interleukin-4 induced;STAT6B;STAT6C;D12S1644;IL-4-STAT;signal transducer and activator of transcription 6;STAT, interleukin4-induced;transcription factor IL-4 STAT |
| Purification | |
| Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| MolecularWeight | |
| Description | |
| Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X, which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.