Rabbit Anti-TRAF2 Polyclonal Antibody-Polyclonal Antibody-Biotyscience

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Rabbit Anti-TRAF2 Polyclonal Antibody

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Citations

Cat No	BSPA-2923
Conjugate
Type	Polyclonal Antibody
Source	Rabbit
Size	1 mg
Application	ELISA; WB; IHC
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS.
Species	Human
Storage	Store at -20 degree. Avoid repeted freeze/thaw cycl.
Synonyms	TRAF2;TNF receptor-associated factor 2;TRAP3;E3 ubiquitin-protein ligase TRAF2;tumor necrosis factor type 2 receptor associated protein 3;tumor necrosis factor type 2 receptor-associated protein 3;TRAP;MGC:45012
Purification
Note	Tis product l is eeze eezeleezeegrrch useeze ly, no useeze huma, apeut agnost apcal.
MolecularWeight
Description
Background	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008]

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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Polyclonal Antibody

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Rabbit Anti-TRAF2 Polyclonal Antibody