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Cat No | BSPA-3025 |
Conjugate | |
Type | Polyclonal Antibody |
Source | Rabbit |
Size | 1 mg |
Application | ELISA; IHC |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS. |
Species | Human |
Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
Synonyms | XRCC6;X-ray repair complementing defective repair in Chinese hamster cells 6;ML8;KU70;TLAA;CTC75;CTCBF;G22P1;X-ray repair cross-complementing protein 6;5-dRP lyase Ku70;5-deoxyribose-5-phosphate lyase Ku70;5-dRP lyase Ku70;70 kDa subunit o |
Purification | |
Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
MolecularWeight | |
Description | |
Background | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and VJ recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |