In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another. Protecting group strategies are usually necessary to prevent undesirable side reactions with the various amino acid side chains.
Biotyscience extensive experience in peptide synthesis technology allows us to handle a wide range of sequences, purity levels and modifications to meet our customers' research needs. Our high success rate means that you will receive customized peptides that can advance your research goals. Regardless of the complexity of the peptide, we offer the same guarantee.
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1. Selection of Amino Acids
The sequence of amino acids determines the exact structure and function of the peptide.
2. Protection of Amino Groups
Protecting groups act as a protective mechanism, guarding specific functional elements on the amino acids and ensuring the selective precision of subsequent reactions.
3. Activation of Carboxyl Groups
This stimulation acts as a crucial trigger, aiding in the vital creation of a peptide bond and indicating another important achievement in the gradual formation of the peptide sequence.
4. Coupling Reactions
Moving ahead in the complex rhythm of peptide production, linking reactions arise as a crucial phase, indicating the successive addition of amino acids to the growing peptide sequence.
5. Deprotection
Once the peptide sequence has been carefully built, the safeguarding protective units worn by amino acids during earlier stages are skillfully taken away. This removal step is a vital introduction to the concluding acts of cleansing and description, playing a central part in revealing the functional units innate in the amino acids.
6. Purification
The unprocessed peptide combination acquired after production is a complicated blend, containing not just the intended peptide but also impurities and secondary outcomes. Cleansing becomes necessary to change this unprocessed mix into a clear and decisive result.
A variety of peptide modifications are available.
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