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Cat No | ADMD-055 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | His |
Size | 1mg |
Application | Immunology |
Format | Liquid |
Purity | >95 %, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Human |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | B1, Bp35, CD20, CVID5, LEU-16, MS4A1, MS4A2, S7 |
Purification | Protein A/G |
Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
MolecularWeight | 10.6 kDa |
Description | |
Background | CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny but not on either early pro-B cells or plasma blasts and plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. Its function is to enable optimal B-cell immune response, specifically against T-independent antigens. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. |